Find De Soto Missouri Hotels, Real Estate, Job Listings, and much more local information on this city guide.

Welcome to De Soto, MO


About De Soto:

De Soto is a city located in Jefferson County, Missouri. As of the 2000 census, the city had a total population of 6,375.

(More Info and Source) De Soto Real Estate

Compare De Soto Hotels, Flights, and Cars

De Soto Job Openings

De Soto QuickSearch

Compare De Soto Travel